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The investigators interpreted the findings as direct pharmacological validation of the NNMT-knockdown phenotype reported earlier in the Kraus 2014 genetic-validation study

With respect to dosage, the average reductions were: 2000 mcg: 71.5% (single data point) 1,000 mcg: 31.8% Although limited data are available for higher dosages, the findings support the efficacy of both oral and non-oral B12 formulations in modulating homocysteine levels

Vitamin B12 repletion in a post-RYGB patient can take 6 to 12 weeks to achieve stable levels

BPC is responsible for the protection of the stomach lining against damage, angiogenesis, and healing through tissue regeneration